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Members News

MGBase members continue to make a strong impact across research, with growing international engagement. Members have contributed to expanding the evidence base through active participation in investigator-led projects and collaborative research initiatives, supporting data collection and driving innovative research questions.

Together, these efforts are enhancing understanding of disease progression, treatment outcomes and patient care, while strengthening MGBase’s reputation as a leading platform for real-world research.

MGBase sub-study - Group leader: Dr Emanuele D'Amico

Comparative effectiveness of C5 inhibitors in generalized AChR+ MG: MGBase registry study

The therapeutic landscape of generalized AChR-positive myasthenia gravis is rapidly evolving with the introduction of complement C5 inhibitors. However, robust real-world comparative data across these agents remain extremely limited. This MGBase sub-study aims to address this critical evidence gap by evaluating the effectiveness of C5 inhibitors in a large, multicenter, real-world cohort. By generating comparative insights on treatment outcomes, this study seeks to directly inform clinical decision-making and optimize therapeutic strategies in everyday practice. Participation from additional centers will be essential to strengthen the analysis and ensure broadly generalizable results.

To learn more about the sub-study or check if your centre is eligible to participate, please visit the Sub-Studies section.

View Sub-Studies

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